hereditary spastic paraplegia 13

MeSH: C537485ORPHA: 100994

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

hereditary spastic paraplegia that is characterized by a pure form of the disease with late onset and has material basis in mutation in the HSPD1 on chromosome 2q33

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hereditary spastic paraplegia 13, sourced from HPO and Orphanet clinical annotations.

Spastic paraplegiaUrinary bladder sphincter dysfunctionUrinary incontinenceHyperreflexiaLower limb spasticitySpastic gaitImpaired vibration sensation in the lower limbsBabinski signAbnormal pyramidal signLower limb muscle weaknessUpper limb hyperreflexiaUrinary urgencyPes cavusScoliosisHearing impairmentRod-cone dystrophy

Classification & Codes

MeSH Code

C537485

Orphanet Code

ORPHA:100994

hereditary spastic paraplegia 13

MeSH	`C537485`
Orphanet	`ORPHA:100994`
Treatments	0 drug(s)
Symptoms on record	16 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO