hereditary spastic paraplegia 19
MeSH: C536856ORPHA: 100999
Overview
hereditary spastic paraplegia that has material basis in variation in the chromosome region 9q
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 19, sourced from HPO and Orphanet clinical annotations.
Pes cavusLower limb muscle weaknessLimb ataxiaImpaired vibration sensation in the lower limbsClonusMuscle spasmLower limb amyotrophyImpaired proprioceptionAbnormal lower-limb motor evoked potentialsFemale sexual dysfunctionMale sexual dysfunctionSpinal cord lesionSpastic gaitUpper limb hyperreflexiaGait disturbanceUrinary urgencyHyperreflexiaLower limb spasticityDegeneration of the lateral corticospinal tractsBabinski signProgressive spastic paraplegia
Classification & Codes
MeSH Code
C536856Orphanet Code
ORPHA:100999hereditary spastic paraplegia 19
| MeSH | C536856 |
| Orphanet | ORPHA:100999 |
| Treatments | 0 drug(s) |
| Symptoms on record | 21 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO