hereditary spastic paraplegia 27
MeSH: C563807ORPHA: 101007
Overview
hereditary spastic paraplegia that has material basis in variation in the chromosome region 10q22.1-q24.1
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 27, sourced from HPO and Orphanet clinical annotations.
Spastic paraplegiaLower limb hyperreflexiaBabinski signSpastic/hyperactive bladderImpaired vibration sensation at anklesDysarthriaDysdiadochokinesisAbnormality of somatosensory evoked potentialsSensorineural hearing impairment
Classification & Codes
MeSH Code
C563807Orphanet Code
ORPHA:101007hereditary spastic paraplegia 27
| MeSH | C563807 |
| Orphanet | ORPHA:101007 |
| Treatments | 0 drug(s) |
| Symptoms on record | 9 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO