hereditary spastic paraplegia 32
MeSH: C566983ORPHA: 171622
Overview
hereditary spastic paraplegia that has material basis in variation in the chromosome region 14q12-q21
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 32, sourced from HPO and Orphanet clinical annotations.
Cerebellar cortical atrophyMild intellectual disabilityAbnormal pons morphologyProgressive spastic paraplegiaLower limb hyperreflexiaSpecific learning disabilityProgressive peripheral neuropathyHypoplasia of the corpus callosumPes cavusProgressive spasticityImpaired vibration sensation in the lower limbsBabinski signGait disturbance
Classification & Codes
MeSH Code
C566983Orphanet Code
ORPHA:171622hereditary spastic paraplegia 32
| MeSH | C566983 |
| Orphanet | ORPHA:171622 |
| Treatments | 0 drug(s) |
| Symptoms on record | 13 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO