hereditary spastic paraplegia 37
MeSH: C567931ORPHA: 171612
Overview
hereditary spastic paraplegia that has material basis in variation in the chromosome region 8p21.1-q13.3
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 37, sourced from HPO and Orphanet clinical annotations.
Degeneration of the lateral corticospinal tractsProgressive spastic paraplegiaHyperreflexiaLower limb spasticityImpaired vibration sensation in the lower limbsBabinski signLower limb muscle weaknessSpinal cord lesionUrinary urgencyGait disturbancePes cavusSpastic gaitClonusMuscle spasmUpper limb hyperreflexiaFatigue
Classification & Codes
MeSH Code
C567931Orphanet Code
ORPHA:171612hereditary spastic paraplegia 37
| MeSH | C567931 |
| Orphanet | ORPHA:171612 |
| Treatments | 0 drug(s) |
| Symptoms on record | 16 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO