hereditary spastic paraplegia 39
MeSH: C567433ORPHA: 139480
Overview
This syndrome is characterised by progressive spastic paraplegia and distal muscle wasting
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 39, sourced from HPO and Orphanet clinical annotations.
Spastic paraplegiaHyperreflexiaLower limb spasticityBabinski signAtrophy of the spinal cordMotor axonal neuropathyGeneralized limb muscle atrophyCerebellar atrophyGait ataxia
Classification & Codes
MeSH Code
C567433Orphanet Code
ORPHA:139480hereditary spastic paraplegia 39
| MeSH | C567433 |
| Orphanet | ORPHA:139480 |
| Treatments | 0 drug(s) |
| Symptoms on record | 9 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO