hereditary spastic paraplegia 63
ORPHA: 401805
Overview
gene (1p13.3) encoding AMP deaminase 2.
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 63, sourced from HPO and Orphanet clinical annotations.
SpasticityHypertoniaHyperreflexiaDelayed gross motor developmentSkeletal muscle atrophyShort statureDecreased body weightScissor gaitAbnormal periventricular white matter morphology
Classification & Codes
Orphanet Code
ORPHA:401805hereditary spastic paraplegia 63
| Orphanet | ORPHA:401805 |
| Treatments | 0 drug(s) |
| Symptoms on record | 9 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO