hereditary spastic paraplegia 72

ORPHA: 401849

Overview

hereditary spastic paraplegia that has material basis in mutation in the REEP2 gene on chromosome 5q31

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hereditary spastic paraplegia 72, sourced from HPO and Orphanet clinical annotations.

RigiditySpastic gaitPes cavusUrinary bladder sphincter dysfunctionPostural tremorMemory impairmentImpaired vibration sensation at anklesAbnormality of mental functionPain

Classification & Codes

Orphanet Code

ORPHA:401849
hereditary spastic paraplegia 72
OrphanetORPHA:401849
Treatments0 drug(s)
Symptoms on record9 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO