hereditary spastic paraplegia 73
ORPHA: 444099
Overview
hereditary spastic paraplegia that has material basis in mutation in the CPT1C gene on chromosome 19q13
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 73, sourced from HPO and Orphanet clinical annotations.
HyperreflexiaLower limb spasticitySpastic gaitDegeneration of the lateral corticospinal tractsBabinski signProgressive spastic paraplegiaUrinary urgencyUrinary incontinenceGait disturbanceImpaired vibration sensation in the lower limbsEMG abnormalityProgressive spastic paraparesisDistal lower limb amyotrophyDistal lower limb muscle weaknessAbnormal lower-limb motor evoked potentialsPes cavus
Classification & Codes
Orphanet Code
ORPHA:444099hereditary spastic paraplegia 73
| Orphanet | ORPHA:444099 |
| Treatments | 0 drug(s) |
| Symptoms on record | 16 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO