hereditary spastic paraplegia 75
ORPHA: 459056
Overview
hereditary spastic paraplegia that has material basis in mutation in the MAG gene on chromosome 19q13
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hereditary spastic paraplegia 75, sourced from HPO and Orphanet clinical annotations.
Intellectual disabilitySpasticitySpastic paraplegiaGlobal developmental delayDysmetriaImpaired vibratory sensationBabinski signAbnormal pyramidal signDistal lower limb amyotrophyAstigmatismHypermetropiaNystagmusHyporeflexiaGeneralized hypotoniaTemporal optic disc pallorTitubation
Classification & Codes
Orphanet Code
ORPHA:459056hereditary spastic paraplegia 75
| Orphanet | ORPHA:459056 |
| Treatments | 0 drug(s) |
| Symptoms on record | 16 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO