Holzgreve-Wagner-Rehder Syndrome
MeSH: C535327ORPHA: 2167
Overview
syndrome characterized by Potter sequence, heart defect, cleft palate, polydactyly, and skeletal defects
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Holzgreve-Wagner-Rehder Syndrome, sourced from HPO and Orphanet clinical annotations.
Posteriorly rotated earsAplasia/Hypoplasia of the lungsRenal hypoplasia/aplasiaAbnormal cardiovascular system morphologyTurricephalyMacrotiaWebbed neckAbnormal rib morphologySingle umbilical arteryJoint stiffnessAbnormal metacarpal morphologyAplasia/Hypoplasia of the corpus callosumAplasia/Hypoplasia of the tongueBifid tongueAbnormal morphology of ulnaAbnormal mesentery morphologyAbnormally ossified vertebraeCleft palateHand polydactylyIntrauterine growth retardationOligohydramnios
Classification & Codes
MeSH Code
C535327Orphanet Code
ORPHA:2167Holzgreve-Wagner-Rehder Syndrome
| MeSH | C535327 |
| Orphanet | ORPHA:2167 |
| Treatments | 0 drug(s) |
| Symptoms on record | 21 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO