Howel–Evans syndrome

MeSH: C536164ORPHA: 2198

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

Tylosis with oesophageal cancer

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Howel–Evans syndrome, sourced from HPO and Orphanet clinical annotations.

Palmoplantar keratodermaNausea and vomitingGastrointestinal hemorrhageAbnormal large intestine morphologyEsophageal neoplasmAscitesWeight lossDysphagiaGastroesophageal refluxPoor suckHepatomegalyPoor appetiteAbnormal esophagus physiologyAbnormal mediastinum morphologyClubbing of toes

Classification & Codes

MeSH Code

C536164

Orphanet Code

ORPHA:2198

Howel–Evans syndrome

MeSH	`C536164`
Orphanet	`ORPHA:2198`
Treatments	0 drug(s)
Symptoms on record	15 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO