Huntington disease-like 2
MeSH: C564708ORPHA: 98934
Overview
Huntington disease-like 2 (HDL2) is a severe neurodegenerative disorder considered part of the neuroacanthocytosis syndromes (see this term) characterized by a triad of movement, psychiatric, and cognitive abnormalities
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Huntington disease-like 2, sourced from HPO and Orphanet clinical annotations.
Personality changesAbnormality of movementAtypical behaviorDementiaGait disturbanceParkinsonismDystoniaHyperreflexiaWeight lossAbnormal cerebral morphologyChoreaCerebral cortical atrophyCaudate atrophyMemory impairmentPrimitive reflexFunctional motor deficitInvoluntary movementsAbnormal corpus striatum morphology
Classification & Codes
MeSH Code
C564708Orphanet Code
ORPHA:98934Huntington disease-like 2
| MeSH | C564708 |
| Orphanet | ORPHA:98934 |
| Treatments | 0 drug(s) |
| Symptoms on record | 18 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO