Huntington's disease
ICD-10: F02.2MeSH: D006816ORPHA: 399
Overview
rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Huntington's disease, sourced from HPO and Orphanet clinical annotations.
Gait disturbanceMental deteriorationHyperreflexiaChoreaAbnormality of eye movementAgitationDepressionAggressive behaviorCompulsive behaviorsDisinhibitionIrritabilityHallucinationsAnxietyApathyDelusionSeizureDystoniaMyoclonusWeight lossBradykinesiaGait imbalanceClumsinessMemory impairmentHypokinesiaGeneralized muscle weaknessInvoluntary movementsAbnormality of the sense of smellPoor fine motor coordinationSpeech articulation difficultiesStaring gazeAngerAbnormally slow thought processAbnormal libidoExcessive daytime somnolenceCerebral atrophyRigidityClonusMutismCaudate atrophyAbnormal cerebral white matter morphologyInability to walkPolyphagiaAbnormal circulating cholesterol concentrationBabinski signImpaired visuospatial constructive cognitionChoking episodesAddictive alcohol useSuicidal ideationDegeneration of the striatumDecreased body mass indexInsomniaOral-pharyngeal dysphagiaDementiaChoreatic diseasePersonality change
Classification & Codes
ICD-10 Code
F02.2MeSH Code
D006816Orphanet Code
ORPHA:399Huntington's disease
| ICD-10 | F02.2 |
| MeSH | D006816 |
| Orphanet | ORPHA:399 |
| Treatments | 0 drug(s) |
| Symptoms on record | 55 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO