hydrops fetalis

ICD-10: P56MeSH: D015160ORPHA: 10412 Treatments Available

Overview

abnormal accumulation of fluid in two or more fetal compartments

Available Treatments (2)

DrugFormStatusCountriesLead Time
Crizotinib
Orphan
Capsule, 200mgFDA Approved510d
eculizumab
Orphan Cold Chain
IV infusion, 10mg/mL concentrate for solutionFDA Approved, EMA Approved914d

Clinical Presentation

Signs and symptoms associated with hydrops fetalis, sourced from HPO and Orphanet clinical annotations.

Abnormality of the neckSmall for gestational ageAscitesNonimmune hydrops fetalisCapillary leakIncreased placental thicknessAbnormality of the kidneyLymphedemaPolyhydramniosPericardial effusionAbnormality of blood and blood-forming tissuesPleural effusionGeneralized edemaAbnormal cardiovascular system morphologySevere infectionAbnormality of the urinary systemAbnormal heart morphologySkeletal dysplasiaNeoplasmAbnormality of the gastrointestinal tractArrhythmiaTwin-to-twin transfusionAbnormality of the lymphatic system

Classification & Codes

ICD-10 Code

P56

MeSH Code

D015160

Orphanet Code

ORPHA:1041
hydrops fetalis
ICD-10P56
MeSHD015160
OrphanetORPHA:1041
Treatments2 drug(s)
Symptoms on record23 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO