hyperprolinemia type 1

ORPHA: 419

Overview

hyperprolinemia that has material basis in homozygous or compound heterozygous mutation in the proline dehydrogenase gene on chromosome 22q11

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hyperprolinemia type 1, sourced from HPO and Orphanet clinical annotations.

ProteinuriaNephropathySeizureProlinuriaHyperprolinemiaSchizophrenia

Classification & Codes

Orphanet Code

ORPHA:419
hyperprolinemia type 1
OrphanetORPHA:419
Treatments0 drug(s)
Symptoms on record6 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
hyperprolinemia type 1 | OrphanDrug