hypertelorism-hypospadias-polysyndactyly syndrome

MeSH: C538332ORPHA: 2211

Overview

Hypertelorism-hypospadias-polysyndactyly syndrome is a very rare syndrome associating an acro-fronto-facio-nasal dysostosis with genitourinary anomalies

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hypertelorism-hypospadias-polysyndactyly syndrome, sourced from HPO and Orphanet clinical annotations.

PachygyriaAbnormal penis morphologyEpispadiasHypospadiasShawl scrotumLarge fontanellesBrachycephalyDelayed cranial suture closureHypertelorismPosteriorly rotated earsLow-set earsWide nasal bridgeDepressed nasal ridgePreaxial hand polydactylyFlat occiputFinger syndactylyBifid scrotumBroad foreheadLong philtrumDownslanted palpebral fissuresGlaucomaPtosisProptosisEyelid colobomaBroad hallux phalanxBroad thumbSacral dimpleLissencephalyEncephalocelePolymicrogyriaAbnormality of neuronal migrationAbnormal cortical gyrationAbnormal toenail morphologyExencephaly

Classification & Codes

MeSH Code

C538332

Orphanet Code

ORPHA:2211
hypertelorism-hypospadias-polysyndactyly syndrome
MeSHC538332
OrphanetORPHA:2211
Treatments0 drug(s)
Symptoms on record34 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO