hypoaldosteronism

ICD-10: E27.4MeSH: D006994ORPHA: 869

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hypoaldosteronism, sourced from HPO and Orphanet clinical annotations.

Palmoplantar keratodermaFailure to thrive in infancyHypernasal speechWeight lossHypoglycemiaVomitingHypoglycemic seizuresHypotensionIncreased circulating ACTH levelShort statureDecreased circulating cortisol levelAlacrimaAdrenal insufficiencyAchalasiaGeneralized hyperpigmentationFeeding difficulties in infancyCoughImpaired cortisol response to corticotropin releasing hormone stimulation testMicrocephalySensorineural hearing impairmentVisual impairmentOptic atrophyKeratoconjunctivitis siccaIntellectual disabilityAtaxiaHypotoniaHyperreflexiaPes cavusRespiratory insufficiencyDevelopmental regressionMotor axonal neuropathyPlantar hyperkeratosisAbnormality of the hypothenar eminenceCorneal ulcerationDecreased circulating aldosterone concentration

Classification & Codes

ICD-10 Code

E27.4

MeSH Code

D006994

Orphanet Code

ORPHA:869
hypoaldosteronism
ICD-10E27.4
MeSHD006994
OrphanetORPHA:869
Treatments0 drug(s)
Symptoms on record35 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO