hypogonadotropic hypogonadism
ORPHA: 432
Overview
hypogonadism characterized by a impaired signalling by gonadotrpin relasing hormone
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with hypogonadotropic hypogonadism, sourced from HPO and Orphanet clinical annotations.
CryptorchidismHypogonadotropic hypogonadismMicropenisPhenotypic abnormalityFemale hypogonadismPrimary amenorrheaImpotenceAbnormality of the voiceSparse body hairDelayed skeletal maturationBreast hypoplasiaEunuchoid habitusWide intermamillary distanceAbsence of secondary sex characteristicsAbsence of pubertal developmentDecreased testicular sizeNon-obstructive azoospermiaIncreased female libidoDecreased serum testosterone concentrationAbnormality of body heightHypoplasia of the uterusDepressionAnxietyGynecomastiaDelayed pubertySecondary amenorrheaOsteopeniaOsteoporosisHypoplasia of the ovaryAbnormality of the dentitionCleft palateHypertelorismGeneralized joint hypermobilityDepressed nasal bridgeCongenital sensorineural hearing impairmentCamptodactylyMale hypogonadismAzoospermia
Classification & Codes
Orphanet Code
ORPHA:432hypogonadotropic hypogonadism
| Orphanet | ORPHA:432 |
| Treatments | 0 drug(s) |
| Symptoms on record | 38 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO