hypopituitarism

MeSH: D007018ORPHA: 95494

Overview

pituitary gland disease characterized by the decreased secretion of one or more of the eight hormones normally produced by the pituitary gland

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with hypopituitarism, sourced from HPO and Orphanet clinical annotations.

Median cleft palateHypopituitarismHypogonadotropic hypogonadismAmenorrheaDepressed nasal ridgeInfertilityDecreased response to growth hormone stimulation testOsteopeniaGrowth delayHypoglycemiaHypotensionDecreased circulating ACTH concentrationPituitary hypothyroidismDecreased testicular sizeAbnormality of secondary sexual hairAplasia/Hypoplasia of the breastsAnterior pituitary agenesisAnterior pituitary hypoplasiaFatigueAbnormal prolactin levelDelayed pubertyPituitary dwarfismConstipationDelayed skeletal maturationOsteoporosis of vertebraeAbsence of secondary sex characteristicsAbnormality of the eyeOptic nerve hypoplasiaSeizureAgenesis of corpus callosumAbsent septum pellucidumHoloprosencephalyDecreased cervical spine mobilityPolydactylyAbnormal digit morphologySevere global developmental delayEctopic posterior pituitaryEctopic anterior pituitary glandSepto-optic dysplasia

Classification & Codes

MeSH Code

D007018

Orphanet Code

ORPHA:95494
hypopituitarism
MeSHD007018
OrphanetORPHA:95494
Treatments0 drug(s)
Symptoms on record39 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO