Hyposmia-nasal and ocular hypoplasia-hypogonadotropic hypogonadism syndrome

ORPHA: 2250

Overview

This syndrome is characterized by the association of severe nasal hypoplasia, hypoplasia of the eyes, hyposmia, hypogeusia and hypogonadotropic hypogonadism

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Hyposmia-nasal and ocular hypoplasia-hypogonadotropic hypogonadism syndrome, sourced from HPO and Orphanet clinical annotations.

CataractTooth malpositionExternal genital hypoplasiaHyposmiaFailure of eruption of permanent teethHypoplasia of penisAplasia of the noseSingle narisHypoplasia of the olfactory bulbAbsent naresCryptorchidismHypogonadotropic hypogonadismHypoplasia of the maxillaChoanal atresiaAnophthalmiaMicrophthalmiaVisual lossIris colobomaBlindnessAmblyopiaGynecomastiaAbdominal wall muscle weaknessAplasia/Hypoplasia involving the noseCleft palateSubmucous cleft hard palateBifid uvulaOptic atrophyDacryocystoceleInguinal herniaHypogonadismAbnormal midface morphologyAnosmia

Classification & Codes

Orphanet Code

ORPHA:2250
Hyposmia-nasal and ocular hypoplasia-hypogonadotropic hypogonadism syndrome
OrphanetORPHA:2250
Treatments0 drug(s)
Symptoms on record32 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO