IgG4-related ophthalmic disease
ORPHA: 449563
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with IgG4-related ophthalmic disease, sourced from HPO and Orphanet clinical annotations.
Abnormality of the orbital regionDacryocystitisPancreatitisIncreased total eosinophil countLymphadenopathyIncreased circulating IgE concentrationAntinuclear antibody positivityEnlarged lacrimal glandsAbnormal fifth cranial nerve morphologyElevated circulating C-reactive protein concentrationAbnormal lacrimal gland morphologyAllergySialadenitisIncreased circulating IgG4 levelPeriorbital edemaAbnormality of infra-orbital nerveAbnormality of the kidneySinusitisAbnormal eyelid morphologyAbnormality of eye movementAbnormal optic nerve morphologyAbnormal lung morphologyRetroperitoneal fibrosisAbnormality of the extraocular musclesMononeuropathyAbnormal ocular adnexa morphologyPalpebral edemaAbnormal morphology of bony orbit of skullProstatitisKeratitisNasolacrimal duct obstructionLymphomaColon cancerAbnormality of the anterior pituitaryNon-Hodgkin lymphomaCholangitisTrigeminal anesthesiaNeoplasm of the lungThyroiditisTrigeminal neuralgiaOrchitisAbnormality of the sphenoid sinus
Classification & Codes
Orphanet Code
ORPHA:449563IgG4-related ophthalmic disease
| Orphanet | ORPHA:449563 |
| Treatments | 0 drug(s) |
| Symptoms on record | 42 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO