IgG4-related submandibular gland disease
ORPHA: 449432
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with IgG4-related submandibular gland disease, sourced from HPO and Orphanet clinical annotations.
Abnormal pancreas morphologyPharyngitisPeriorbital edemaProstatitisAbnormal bronchus morphologyAutoimmunityIncreased circulating IgG concentrationAbnormality of the submandibular glandsIncreased circulating IgG4 levelXerostomiaIncreased total eosinophil countLymphadenopathyIncreased circulating IgE concentrationReduced circulating complement concentrationEnlarged lacrimal glandsAbnormal salivary gland morphologyIncreased circulating immunoglobulin concentrationSialadenitisAbnormality of the kidneyRenal insufficiencyFacial edemaAbnormality of the thyroid glandRetroperitoneal fibrosisEnlargement of parotid glandCholangitis
Classification & Codes
Orphanet Code
ORPHA:449432IgG4-related submandibular gland disease
| Orphanet | ORPHA:449432 |
| Treatments | 0 drug(s) |
| Symptoms on record | 25 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO