IMAGe syndrome

ORPHA: 85173

Overview

syndrome that is characterized by intrauterine growth restriction, metaphyseal dysplasia, adrenal hypoplasia congenita, genital abnormalities and has physical basis in heterozygous mutation in the CDKN1C gene

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with IMAGe syndrome, sourced from HPO and Orphanet clinical annotations.

CryptorchidismHypospadiasAbnormality of the genital systemHydronephrosisHypogonadismLow-set earsAdrenal hypoplasiaHypotoniaIntrauterine growth retardationFrontal bossingMicromeliaDepressed nasal bridgeMetaphyseal dysplasia

Classification & Codes

Orphanet Code

ORPHA:85173
IMAGe syndrome
OrphanetORPHA:85173
Treatments0 drug(s)
Symptoms on record13 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO