isolated aniridia

ORPHA: 250923

Overview

Isolated aniridia is a congenital bilateral ocular malformation characterized by the complete or partial absence of the iris

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with isolated aniridia, sourced from HPO and Orphanet clinical annotations.

AniridiaVisual lossNystagmusReduced visual acuityHypoplasia of the irisHypoplasia of the foveaAplasia/Hypoplasia of the maculaStrabismusGlaucomaCataractRed-green dyschromatopsiaPeters anomalyEctopia lentisKeratoconjunctivitis siccaFundus hypopigmentationCorneal opacityCorneal neovascularizationAbnormal full-field electroretinogramAbnormal multifocal electroretinogramAbnormal foveal pit on macular OCTLimbal stem cell deficiencyPtosisMicrophthalmiaOptic nerve hypoplasiaPhotophobiaMicrospherophakiaLens coloboma

Classification & Codes

Orphanet Code

ORPHA:250923
isolated aniridia
OrphanetORPHA:250923
Treatments0 drug(s)
Symptoms on record27 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
isolated aniridia | OrphanDrug