isolated growth hormone deficiency
ORPHA: 631
Overview
hypopituitarism characterized by abnormally low levels, absence or impaired function of growth hormone in the absence of abnormalities in other pituitary hormones
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with isolated growth hormone deficiency, sourced from HPO and Orphanet clinical annotations.
Anterior hypopituitarismGrowth delayDelayed skeletal maturationShort statureDoll-like faciesDelayed pubertyDecreased response to growth hormone stimulation testAbnormally high-pitched voiceNeonatal hypoglycemiaDecreased muscle massDepressed nasal bridgeProlonged neonatal jaundiceSparse hairProminent foreheadAbdominal obesityDecreased circulating serum insulin-like growth factor 1 concentrationPremature skin wrinklingGenu valgumMicrophallus
Classification & Codes
Orphanet Code
ORPHA:631isolated growth hormone deficiency
| Orphanet | ORPHA:631 |
| Treatments | 0 drug(s) |
| Symptoms on record | 19 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO