isolated sedoheptulokinase deficiency

ORPHA: 440713

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with isolated sedoheptulokinase deficiency, sourced from HPO and Orphanet clinical annotations.

Flexion contractureArthrogryposis multiplex congenitaNeonatal asphyxiaInguinal herniaRenal insufficiencyAbnormal renal tubule morphologyLarge fontanellesMacrocephalyHigh foreheadShallow orbitsHypotelorismHip dysplasiaCholestasisPortal hypertensionDiastasis rectiBreech presentationAnemiaVentriculomegalySteatorrheaCholestatic liver diseaseShort statureHypochromic microcytic anemiaSevere postnatal growth retardationAbnormal CNS myelinationPostprandial hyperglycemiaHepatitisSubcortical cerebral atrophyAbnormality of globe location

Classification & Codes

Orphanet Code

ORPHA:440713
isolated sedoheptulokinase deficiency
OrphanetORPHA:440713
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO