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isotretinoin-like syndrome

MeSH: C535542ORPHA: 2306

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

Isotretinoin-like syndrome is a phenocopy of the isotretinoin embryopathy

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with isotretinoin-like syndrome, sourced from HPO and Orphanet clinical annotations.

MicrotiaInguinal herniaCleft palateHydrocephalusMicrocephalyMicrognathiaPreauricular skin tagAtresia of the external auditory canalAnteverted naresUpslanted palpebral fissureAbnormal posterior cranial fossa morphologyIntrauterine growth retardationPatent ductus arteriosusBicuspid aortic valveAortic valve stenosisConotruncal defectAbnormal cardiac ventricle morphologyGastroesophageal refluxAbnormal cardiac atrium morphologyPersistent left superior vena cavaBilateral sensorineural hearing impairmentAplasia/Hypoplasia of the inner earPostnatal growth retardationMild global developmental delayAbnormality of the pulmonary veinsFeeding difficultiesAbnormal aortic arch morphologyAnotia

Classification & Codes

MeSH Code

C535542

Orphanet Code

ORPHA:2306
isotretinoin-like syndrome
MeSHC535542
OrphanetORPHA:2306
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO