Japanese encephalitis

MeSH: D004672ORPHA: 79139

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

infection of the brain caused by the Japanese encephalitis virus

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Japanese encephalitis, sourced from HPO and Orphanet clinical annotations.

FeverEEG abnormalityInfectious encephalitisFacial grimacingMask-like faciesVomitingAnorexiaBilateral tonic-clonic seizureHeadacheCogwheel rigidityIncreased intracranial pressureIncreased CSF protein concentrationSkeletal muscle atrophyMyalgiaDecreased motor nerve conduction velocityEMG: chronic denervation signsParalysisIncreased circulating IgM levelFunctional motor deficitReduced consciousnessPaucity of anterior horn motor neuronsDistal lower limb muscle weaknessWeakness due to upper motor neuron dysfunctionIncreased circulating immunoglobulin concentrationIncreased total neutrophil countCSF pleocytosisFatigueFocal T2 hyperintense thalamic lesionChillsHyperintensity of MRI T2 signal of the spinal cordCSF lymphocytic pleiocytosisNystagmusAtypical behaviorComaChoreoathetosisHypertoniaMeningitisDystoniaMyoclonusTremorTalipes equinovarusDiarrheaAbdominal painAbnormal cerebral morphologyAbnormality of extrapyramidal motor functionRespiratory distressStatus epilepticusOpisthotonusCerebral edemaRespiratory paralysisAbnormal caudate nucleus morphologyAbnormal midbrain morphologyLanguage impairmentAbnormal pattern of respirationGenu recurvatumHyponatremiaElbow flexion contractureExcessive salivationAbnormal pons morphologyAbnormal pupillary light reflexLimited extraocular movementsDistal upper limb muscle weaknessOpsoclonusMuscle fibrillationMuscle flaccidityFacial palsyAbnormal thalamus morphologyEEG with burst suppressionSevere intellectual disabilityFocal motor seizureInterictal epileptiform activityFacial ticsIrregular respirationAbnormality of the internal capsuleRigorsStiff neckPill-rolling tremorEyelid fasciculationInappropriate antidiuretic hormone secretionAbnormal substantia nigra morphologyCognitive impairmentPulmonary edema

Classification & Codes

MeSH Code

D004672

Orphanet Code

ORPHA:79139

Japanese encephalitis

MeSH	`D004672`
Orphanet	`ORPHA:79139`
Treatments	0 drug(s)
Symptoms on record	82 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO