juvenile Huntington disease

ORPHA: 248111

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

Juvenile Huntington disease (JHD) is a form of Huntington disease (HD; see this term), characterized by onset of signs and symptoms before 20 years of age

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with juvenile Huntington disease, sourced from HPO and Orphanet clinical annotations.

Atypical behaviorDepressionDementiaIrritabilityHyperactivitySeizureAtaxiaDystoniaHyperreflexiaWeight lossRigidityGait ataxiaBradykinesiaChoreaBroad-based gaitAbnormal cerebral white matter morphologyAbnormal involuntary eye movementsOral motor hypotoniaNeuronal loss in basal gangliaCerebellar atrophyMyoclonusProgressive cerebellar ataxiaVentriculomegalyCerebellar vermis atrophy

Classification & Codes

Orphanet Code

ORPHA:248111

juvenile Huntington disease

Orphanet	`ORPHA:248111`
Treatments	0 drug(s)
Symptoms on record	24 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO