juvenile onset Parkinson disease 19A
ORPHA: 391411
Overview
Parkinson's disease that has material basis in homozygous mutation in the DNAJC6 gene on chromosome 1p31
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with juvenile onset Parkinson disease 19A, sourced from HPO and Orphanet clinical annotations.
Inability to walkSlowed slurred speechIntellectual disabilitySeizureHyporeflexiaWeak voicePes cavusGait ataxiaAkinesiaScoliosisInvoluntary movementsAbnormal pyramidal signShort stepped shuffling gaitLeg muscle stiffnessFatigueBrain atrophyAbnormal nervous system physiologyAbnormality of movementMyoclonusShuffling gaitAnarthriaHypomimic faceDystoniaRigidityBradykinesiaPostural instabilityResting tremor
Classification & Codes
Orphanet Code
ORPHA:391411juvenile onset Parkinson disease 19A
| Orphanet | ORPHA:391411 |
| Treatments | 0 drug(s) |
| Symptoms on record | 27 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO