Kleine-Levin syndrome
ICD-10: G47.8MeSH: D017593ORPHA: 33543
Overview
recurrent hypersomnia that is characterized by recurring periods of excessive amounts of sleep and altered behavior
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Kleine-Levin syndrome, sourced from HPO and Orphanet clinical annotations.
ConfusionAmplification of sexual behaviorEpisodic hypersomniaCognitive impairmentPhotophobiaAgitationDepressionIrritabilityAnxietyApathyHyperhidrosisFeverAbnormal speech patternHeadachePolyphagiaPoor hand-eye coordinationRepetitive compulsive behaviorTransient global amnesiaAbnormal brain FDG positron emission tomographyParageusiaParosmiaAbnormal eating behaviorBlurred visionDelusionSlurred speechPolydipsiaNauseaMutismHypnagogic hallucinationPoor appetiteSleep paralysisSweet cravingHot flashesDecreased libidoDerealization
Classification & Codes
ICD-10 Code
G47.8MeSH Code
D017593Orphanet Code
ORPHA:33543Kleine-Levin syndrome
| ICD-10 | G47.8 |
| MeSH | D017593 |
| Orphanet | ORPHA:33543 |
| Treatments | 0 drug(s) |
| Symptoms on record | 35 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO