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Laing early-onset distal myopathy

ORPHA: 59135

Contents

  1. 1. Available Treatments
  2. 2. Clinical Presentation
  3. 3. Classification & Codes

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Laing early-onset distal myopathy, sourced from HPO and Orphanet clinical annotations.

Foot dorsiflexor weaknessToe extensor amyotrophyHigh palateNeck muscle weaknessGait disturbanceAbnormal calf musculature morphologyDistal muscle weaknessScoliosisProgressive muscle weaknessMyalgiaMinicore myopathyType 1 muscle fiber predominanceTalipes cavus equinovarusMildly elevated creatine kinaseAbnormal mitochondria in muscle tissueWeakness of orbicularis oculi muscleDilated cardiomyopathyEMG: myopathic abnormalitiesProximal lower limb muscle weakness

Classification & Codes

Orphanet Code

ORPHA:59135
Laing early-onset distal myopathy
OrphanetORPHA:59135
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO