Lamb-Shaffer syndrome

ORPHA: 313892

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Lamb-Shaffer syndrome, sourced from HPO and Orphanet clinical annotations.

Intellectual disabilityMotor delayDelayed speech and language developmentHyperplasia of the maxillaNarrow palateStrabismusMyopiaExotropiaOptic atrophyDental crowdingAnxietyPectus carinatumHypotoniaFrontal bossingExaggerated median tongue furrowLumbar hyperlordosisVertebral fusion2-3 toe syndactylyThoracic kyphoscoliosisAbnormal brain morphologyAbnormality of the genital systemAggressive behaviorMotor stereotypySeizureMitral regurgitationGastroesophageal refluxScoliosisButterfly vertebraeAttention deficit hyperactivity disorderFeeding difficultiesSelf-injurious behavior

Classification & Codes

Orphanet Code

ORPHA:313892
Lamb-Shaffer syndrome
OrphanetORPHA:313892
Treatments0 drug(s)
Symptoms on record31 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
Lamb-Shaffer syndrome | OrphanDrug