Laryngeal cleft
ORPHA: 2004
Overview
laryngo-tracheo-esophageal cleft (LC) is a congenital malformation characterized by an abnormal, posterior, sagittal communication between the larynx and the pharynx, possibly extending downward between the trachea and the esophagus
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Laryngeal cleft, sourced from HPO and Orphanet clinical annotations.
Laryngeal cleftCyanosisLaryngomalaciaAbnormality of the voiceHoarse cryDyspneaRecurrent respiratory infectionsAspirationStridorCoughChoking episodesImpaired oropharyngeal swallow responseNeonatal respiratory distress
Classification & Codes
Orphanet Code
ORPHA:2004Laryngeal cleft
| Orphanet | ORPHA:2004 |
| Treatments | 0 drug(s) |
| Symptoms on record | 13 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO