Leber hereditary optic neuropathy
MeSH: D029242ORPHA: 1041 Treatment Available
Overview
Human disease
Available Treatments (1)
| Drug | Form | Status | Countries | Lead Time |
|---|---|---|---|---|
| idebenone Orphan | oral tablet, 150 mg | EMA Approved | 9 | 21d |
Clinical Presentation
Signs and symptoms associated with Leber hereditary optic neuropathy, sourced from HPO and Orphanet clinical annotations.
Slow decrease in visual acuityMitochondrial respiratory chain defectsProgressive visual lossCentrocecal scotomaCentral scotomaBlurred visionOptic atrophyRetinal telangiectasiaRetinal vascular tortuosityAbnormal electroretinogramColor vision defectAbnormality of visual evoked potentialsAtaxiaPostural tremorMyopathyVentricular preexcitationPeripheral neuropathyArrhythmiaRetinal nerve fiber edemaReduced contrast sensitivity
Classification & Codes
MeSH Code
D029242Orphanet Code
ORPHA:104Leber hereditary optic neuropathy
| MeSH | D029242 |
| Orphanet | ORPHA:104 |
| Treatments | 1 drug(s) |
| Symptoms on record | 20 signs |
| Status | published |
Treatment Summary
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO