limbic encephalitis with NMDA receptor antibodies
ORPHA: 217253
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with limbic encephalitis with NMDA receptor antibodies, sourced from HPO and Orphanet clinical annotations.
Atypical behaviorShort attention spanSeizureConfusionMemory impairmentCSF pleocytosisAnti-NMDA receptor antibody positivityCSF anti-NMDA receptor antibody positivityHallucinationsAnxietyDelusionFeverVomitingDiarrheaHeadacheInvoluntary movementsEEG with temporal sharp slow wavesOvarian teratomaAbnormal autonomic nervous system physiologyDyskinesiaManiaInsomniaPsychosisAgitationDepressionMotor stereotypyChoreoathetosisOrthostatic hypotensionDystoniaMyoclonusRigidityChoreaStatus epilepticusOpisthotonusGeneralized-onset seizureMutismOrofacial dyskinesiaLoss of speechLanguage impairmentExcessive salivationFocal-onset seizureNo social interactionOculogyric crisisOrthostatic tachycardiaAbnormal sudomotor regulationDeliriumAmplification of sexual behaviorNeuroblastomaHodgkin lymphomaNeoplasm of the breastNeoplasm of the thymusNeoplasm of the lungTesticular teratoma
Classification & Codes
Orphanet Code
ORPHA:217253limbic encephalitis with NMDA receptor antibodies
| Orphanet | ORPHA:217253 |
| Treatments | 0 drug(s) |
| Symptoms on record | 53 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO