localized epidermolysis bullosa simplex
ORPHA: 79400
Overview
epidermolysis bullosa simplex that is characterized by skin blistering that begins anytime between childhood and adulthood and is usually limited to the hands and feet
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with localized epidermolysis bullosa simplex, sourced from HPO and Orphanet clinical annotations.
PruritusLamina lucida cleavagePalmoplantar blisteringFocal friction-related palmoplantar hyperkeratosisSkin fragility with non-scarring blisteringAbnormal blistering of the skinFoot painHeat intoleranceParesthesiaAcute episodes of neuropathic symptomsUpper limb painSkin plaqueHyperhidrosisPlantar hyperkeratosisPalmar hyperkeratosisErosion of oral mucosaSkin erosionMiliaAtrophic scarsNail dystrophyErythematous papuleOral mucosal blisters
Classification & Codes
Orphanet Code
ORPHA:79400localized epidermolysis bullosa simplex
| Orphanet | ORPHA:79400 |
| Treatments | 0 drug(s) |
| Symptoms on record | 22 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO