localized scleroderma
MeSH: D012594ORPHA: 90289
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with localized scleroderma, sourced from HPO and Orphanet clinical annotations.
Thickened skinArthralgiaLocalized skin lesionStiff skinCutaneous sclerotic plaqueAbnormality of the dentitionAbnormal upper lip morphologyFacial asymmetryAbnormality of visionUveitisDental malocclusionHyperpigmentation of the skinHypopigmented skin patchesArthritisFlexion contractureGastroesophageal refluxMigrainePatchy alopeciaHeadacheAutoimmunityMyopathyAbnormal cheek morphologyShort dental rootProgressive loss of facial adipose tissueErythemaHemifacial atrophyAbnormal facial skeleton morphologyErythematous plaqueAbnormality of the musculoskeletal systemFasciitisUpper limb asymmetryInfra-orbital creaseSclerosis of finger phalanxAbnormality of the kidneyAbnormality of the noseDeeply set eyeProptosisAbnormality of the nervous systemHashimoto thyroiditisVitiligoSeizureStrokeAbnormality of the cardiovascular systemAbnormality of the respiratory systemFocal impaired awareness seizureVasculitisSkeletal muscle atrophyAbnormal bone structureAbnormal blistering of the skinAbnormal skin adnexa morphologyArrhythmiaAbnormality on pulmonary function testingRaynaud phenomenonEsophagitisSkin erosion
Classification & Codes
MeSH Code
D012594Orphanet Code
ORPHA:90289localized scleroderma
| MeSH | D012594 |
| Orphanet | ORPHA:90289 |
| Treatments | 0 drug(s) |
| Symptoms on record | 55 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO