Loeffler endocarditis
ORPHA: 75566
Overview
restrictive cardiomyopathy that affects the endocardium and occurs with white blood cell proliferation, specifically of eosinophils
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Loeffler endocarditis, sourced from HPO and Orphanet clinical annotations.
Restrictive cardiomyopathyIncreased total eosinophil countAbnormal thrombosisMyocardial eosinophilic infiltrationCongestive heart failureAbnormal heart valve morphologyLeft ventricular hypertrophyWeight lossPalpitationsDyspneaFatigueLeft ventricular diastolic dysfunctionAbnormal cardiomyocyte morphologyChest painMitral regurgitationMyocardial fibrosisEndocardial fibrosisT-wave inversionArrhythmiaComplete right bundle branch blockCoughAbnormal morphology of the chordae tendinae of the mitral valveLeft atrial enlargementAbnormal tricuspid chordae tendinae morphologyAortic valve stenosisAortic regurgitationPericarditis
Classification & Codes
Orphanet Code
ORPHA:75566Loeffler endocarditis
| Orphanet | ORPHA:75566 |
| Treatments | 0 drug(s) |
| Symptoms on record | 27 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO