Loeys-Dietz syndrome

MeSH: D055947ORPHA: 60030

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Loeys-Dietz syndrome, sourced from HPO and Orphanet clinical annotations.

Joint hypermobilityPatent ductus arteriosusPes planusVascular dilatationAortic dissectionAortic aneurysmArterial tortuosityArterial dissectionUterine ruptureTall statureCleft palateBifid uvulaOrofacial cleftMalar flatteningHypertelorismMicrognathiaBlue scleraeEczematoid dermatitisAtypical scarring of skinStriae distensaeArachnodactylyCraniosynostosisTalipes equinovarusAsthmaScoliosisCamptodactyly of fingerMyopiaPectus excavatumPectus carinatumThin skinBruising susceptibilityJoint dislocationMitral regurgitationCardiac arrestAbnormal bleedingSpontaneous pneumothoraxEosinophilic infiltration of the esophagus

Classification & Codes

MeSH Code

D055947

Orphanet Code

ORPHA:60030
Loeys-Dietz syndrome
MeSHD055947
OrphanetORPHA:60030
Treatments0 drug(s)
Symptoms on record37 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO