Majeed syndrome

MeSH: C537839ORPHA: 77297

Overview

Majeed syndrome is a rare genetic multisystemic disorder characterized by the triad of chronic recurrent multifocal osteomyelitis, congenital dyserythropoietic anemia, and variable transient inflammatory dermatosis

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Majeed syndrome, sourced from HPO and Orphanet clinical annotations.

Weight lossFeverBone painOsteomyelitisArthralgiaMetaphyseal irregularityCachexiaCongenital hypoplastic anemiaHypochromic microcytic anemiaAbnormal bone marrow cell morphologyAbnormal inflammatory responsePapulePustuleEdemaAcneFailure to thriveSplenomegalyIncreased total leukocyte countHepatomegalyHeadacheMyalgiaIncreased bone mineral densitySynovitisProteinuriaFlexion contractureMalabsorptionPulmonary infiltratesIncreased susceptibility to fracturesMicroscopic hematuriaInflammatory abnormality of the skinCoughGlomerulopathy

Classification & Codes

MeSH Code

C537839

Orphanet Code

ORPHA:77297
Majeed syndrome
MeSHC537839
OrphanetORPHA:77297
Treatments0 drug(s)
Symptoms on record32 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO