Mal de Meleda

ORPHA: 87503

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Mal de Meleda, sourced from HPO and Orphanet clinical annotations.

Palmoplantar keratodermaAbnormality of the handAbnormal foot morphologyNonepidermolytic palmoplantar hyperkeratosisInflammatory abnormality of the skinSuperficial dermal perivascular inflammatory infiltrateHyperhidrosisAutoamputationFlexion contractureHyperkeratosis with erythemaDiffuse palmoplantar hyperkeratosisErythemaEpidermal acanthosisIchthyosisLichenoid skin lesion

Classification & Codes

Orphanet Code

ORPHA:87503
Mal de Meleda
OrphanetORPHA:87503
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO