maple syrup urine disease

MeSH: D008375ORPHA: 511

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with maple syrup urine disease, sourced from HPO and Orphanet clinical annotations.

Abnormality of the pharynxIntellectual disabilitySeizureAtaxiaHypotoniaGlobal developmental delayReduced tendon reflexesAbnormality of the voiceRespiratory insufficiencyHemiplegia/hemiparesisElevated circulating branched chain amino acid concentration

Classification & Codes

MeSH Code

D008375

Orphanet Code

ORPHA:511
maple syrup urine disease
MeSHD008375
OrphanetORPHA:511
Treatments0 drug(s)
Symptoms on record11 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO