maternal 14q32.2 hypermethylation syndrome

ORPHA: 254534

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with maternal 14q32.2 hypermethylation syndrome, sourced from HPO and Orphanet clinical annotations.

Mild intellectual disabilityGlobal developmental delayPolyhydramniosThoracic hypoplasiaLarge placentaCoat hanger sign of ribsFeeding difficulties in infancyHypotoniaLarge for gestational ageDiastasis rectiPoor suckPostnatal growth retardationSmall for gestational ageUmbilical herniaOmphaloceleOvergrowthAbnormal heart morphologyVentricular septal defectDelayed gross motor development

Classification & Codes

Orphanet Code

ORPHA:254534
maternal 14q32.2 hypermethylation syndrome
OrphanetORPHA:254534
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO