maternal uniparental disomy of chromosome 2

ORPHA: 96179

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with maternal uniparental disomy of chromosome 2, sourced from HPO and Orphanet clinical annotations.

Intrauterine growth retardationAbnormality of the amniotic fluidPostnatal growth retardationHypothyroidismOligohydramniosNeonatal respiratory distressAbnormality of the ankleElevated amniotic fluid alpha-fetoproteinContractures of the large jointsChordeeHypospadiasRenal insufficiencyRenal dysplasiaRetinal degenerationDecreased response to growth hormone stimulation testPreaxial hand polydactylyPremature birthPes planusPulmonary hypoplasiaSkeletal dysplasiaImmunodeficiencyClinodactyly of the 5th fingerRespiratory infections in early lifePremature ovarian insufficiencyC1-C2 vertebral abnormalityBilateral cryptorchidismGlobal developmental delay

Classification & Codes

Orphanet Code

ORPHA:96179
maternal uniparental disomy of chromosome 2
OrphanetORPHA:96179
Treatments0 drug(s)
Symptoms on record27 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO