maternally-inherited spastic paraplegia
ORPHA: 320360
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with maternally-inherited spastic paraplegia, sourced from HPO and Orphanet clinical annotations.
Impaired vibration sensation in the lower limbsProgressive spastic paraplegiaLower limb painGait disturbanceHyperreflexiaLower limb spasticityPeripheral axonal neuropathyDistal lower limb muscle weaknessDiabetes mellitusAbnormal cerebellum morphologyCardiomyopathyBabinski signSupraventricular arrhythmiaAbnormal pyramidal signLeg muscle stiffness
Classification & Codes
Orphanet Code
ORPHA:320360maternally-inherited spastic paraplegia
| Orphanet | ORPHA:320360 |
| Treatments | 0 drug(s) |
| Symptoms on record | 15 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO