Matthew-Wood syndrome

ORPHA: 2470

Overview

autosomal genetic disease that is characterized by microphthalmia or anophthalmia, pulmonary agenesis, and diaphragmatic defect

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Matthew-Wood syndrome, sourced from HPO and Orphanet clinical annotations.

AnophthalmiaMicrophthalmiaIntellectual disabilityCongenital diaphragmatic herniaAbnormal lung morphologyPulmonary hypoplasiaAbnormal cardiovascular system morphologyCryptorchidismVesicoureteral refluxHorseshoe kidneyRenal hypoplasiaAbnormality of the uterusLow-set earsHypotoniaFailure to thriveIntrauterine growth retardationAnnular pancreasAbnormal spleen morphologyAplasia/Hypoplasia of the pancreasDuodenal stenosis

Classification & Codes

Orphanet Code

ORPHA:2470
Matthew-Wood syndrome
OrphanetORPHA:2470
Treatments0 drug(s)
Symptoms on record20 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO