Megalocornea-mental retardation syndrome

MeSH: C536143ORPHA: 24791 Treatment Available

Overview

medical condition

Available Treatments (1)

DrugFormStatusCountriesLead Time
atropine sulfate
ophthalmic solution 0.5%, 1%FDA Approved77d

Clinical Presentation

Signs and symptoms associated with Megalocornea-mental retardation syndrome, sourced from HPO and Orphanet clinical annotations.

Joint hypermobilityMicrognathiaMegalocorneaIntellectual disabilityHypotoniaGlobal developmental delayFrontal bossingAbnormal speech patternAbnormality of immune system physiologyOpen mouthHigh palateEpicanthusHypertelorismWide nasal bridgeDownslanted palpebral fissuresMyopiaAbnormal anterior chamber morphologyMotor stereotypyTapered fingerSeizureScoliosisKyphosisGenu varumShort statureHypoplasia of the irisMetatarsus valgusIridodonesisEverted lower lip vermilionMicrocephalyMacrocephalyShort philtrumSensorineural hearing impairmentProtruding earAstigmatismNystagmusHypothyroidismOsteopeniaAtaxiaEEG abnormalityHypercholesterolemiaUnderdeveloped supraorbital ridges

Classification & Codes

MeSH Code

C536143

Orphanet Code

ORPHA:2479
Megalocornea-mental retardation syndrome
MeSHC536143
OrphanetORPHA:2479
Treatments1 drug(s)
Symptoms on record41 signs
Statuspublished

Treatment Summary

Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO