OrphanDrug
OrphanDrug
Pharma Knowledge Base

Melkersson-Rosenthal syndrome

MeSH: D008556ORPHA: 2483

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip - cheilitis granulomatosis) and the development of folds and furrows in the tongue (fissured tongue)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Melkersson-Rosenthal syndrome, sourced from HPO and Orphanet clinical annotations.

Mask-like faciesEdemaCranial nerve paralysisOligosacchariduriaInflammatory abnormality of the skinPeriorbital edemaCheilitisMacroglossiaFurrowed tongueFacial palsyNystagmusFeverLymphadenopathyAbnormal autonomic nervous system physiology

Classification & Codes

MeSH Code

D008556

Orphanet Code

ORPHA:2483
Melkersson-Rosenthal syndrome
MeSHD008556
OrphanetORPHA:2483
Treatments0 drug(s)
Symptoms on record14 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO